Cocaine:
Cocaine is an antagonist because it blocks three important neurotransmitters: dopamine, serotonin, and norepinephrine. These transmitters affect either our mood, arousal, attention, emotion, etc., so with them blocked, our body won't react normally with these feelings. This can lead into a state of depression unless cocaine is in the body fulfilling the craving for the "rush" feeling from euphoria. Long-term use of cocaine can cause lethargy, psychosis, depression, and it is fatal if a person overdosed. If a person is having an overdose try to calm them down by bringing them into a quiet room, and don't respond to their delusions. If nothing is working you need to call a doctor and bring them in.
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